Antibiotic Susceptibility Patterns of Uropathogenic Organisms in Febrile Under-Five Children at Federal Medical Centre, Owerri, Nigeria:Implications for Empiric Treatment Strategies

¹Nwigwe U. M., ²Esezobor C. I., ¹Iregbu F. U. and ³Ushie S. N.

 ¹Federal   University Teaching Hospital Owerri

  ²Lagos University Teaching Hospital Lagos State

 ³Nnamdi Azikiwe University Teaching Hospital Nnewi

ABSTRACT

Urinary tract infections (UTIs) in under-five children are often under-diagnosed, leading to potential adverse outcomes. This study investigates the antibiotic susceptibility patterns of uropathogenic organisms isolated from febrile under-five children at the Federal Medical Centre, Owerri, Nigeria. The research highlights the dynamic nature of antibiotic sensitivity, emphasizing the need for regular assessments and prudent antibiotic use. Findings reveal varying susceptibility to commonly used antibiotics, necessitating a reevaluation of empirical choices. Amikacin, gentamicin, and levofloxacin demonstrate high sensitivity, while co-trimoxazole and co-amoxiclav exhibit lower effectiveness. The study underscores the importance of regional considerations in managing UTIs and advocates for improved antibiotic stewardship.

Keywords: Uropathogenic organisms, febrile under-five children, antibiotic susceptibility, urinary tract infections and Nigeria

CITE AS: Nwigwe U. M., Esezobor C. I., Iregbu F. U. and Ushie S. N. (2024). Antibiotic Susceptibility Patterns of Uropathogenic Organisms in Febrile Under-Five Children at Federal Medical Centre, Owerri, Nigeria:Implications for Empiric Treatment Strategies. IAA Journal of Biological Sciences 12(1):1-10. https://doi.org/10.59298/IAAJB/2024/121.11.19