TOPIC
BAC of Mango kernel seed, Avocado pear seed and Velvet tamarind
shell
of allergic diseases. Despite the enormous medical importance of this drug, its released into
the environment through industrial effluents, consumption, or as unused or expired
products poses adverse effects to exposed biota and man. Development of effective method
for the adsorption and elimination of Chlorpherinamine and other pharmaceutical drugs has
been a common interest to researchers. This study was planned to investigate the effect of
pH on chlorpheniramine adsorption using oxidized activated carbons (OAC), hydrophobic
activated carbons (HAC) and basic activated carbons (BAC) of Mango kernel seed, Avocado
pear seed and Velvet tamarind shell. The adsorptions of chlorpheniramine, a basic drug on
these carbons were investigated at different pH. Drug adsorption depends mainly on solution
pH and the adsorbent surface nature, and initial pH 7 was found optimal for the removal of
this drug. Equilibrium adsorption was reached faster on HAC and OAC than on BAC with
kinetic adsorption data following well pseudo second order model much better than pseudo
first order and intra-particle diffusion. Equilibrium adsorption data follow well the Langmuir
model than the Freundlich model. The Chlorpheniramine uptake follows the order: HAC >
OAC > BAC for mango kernel seed and avocado pear seed while that of velvet tamarind shell
was: OAC > HAC > BAC. From the result of this study, OAC, HAC, BAC showed good capability
for Chlorpheniramine removal from pharmaceutical waste and hence can be used to curb
environmental pollution emanating from liquid pharmaceutical waste containing
chlorpheniramine.
Keywords: Chlorpheniramine, pharmaceutical waste, drug adsorption, activated carbons
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PUBLISHED
2023-01-11
HOW TO CITE
Iloh Emmanuel Onyema (2023).Effect of pH on Chlorpheniramine adsorption using OAC, HAC and
BAC of Mango kernel seed, Avocado pear seed and Velvet tamarind
shell. IAA Journal of Applied Sciences 9(1):66-73.